Defensa y Justicia faced Unión de Santa Fe at Estadio Norberto Tomaghello on March 21, 2026 at 20:45 UTC. The match was part of the Liga Profesional de Fútbol, Apertura. Defensa y Justicia played with a 3-4-3, while Unión de Santa Fe used a 4-4-2. Goals from Juan Manuel Gutiérrez and Lucas Souto gave Defensa y Justicia the win. The match was a clash between two teams fighting to maintain their position in the league table.